USP4 Flag&His Tag Protein, Human
SKU: 61998181160

USP4 Flag&His Tag Protein, Human

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Description

USP4 Flag&His Tag Protein, HumanProduct Specification Species Human Synonyms UBP4, UNP, UNPH Accession Q13107 Amino Acid Sequence Ala2 Asn963

Product Specification


Species Human
Synonyms UBP4, UNP, UNPH
Accession Q13107
Amino Acid Sequence

Ala2-Asn963 DYKDDDDKAEGGGCRERPDAETQKSELGPLMRTTLQRGAQWYLIDSRWFKQWKKYVGFDSWDMYNVGEHNLFPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPTEAWNKLLNWYGCVEGQQPIVRKVVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERETRLWNKYMSNTYEQLSKLDNTVQDAGLYQGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRNFTTSPKSSASPYSSVSASLIANGDSTSTCGMHSSGVSRGGSGFSASYNCQEPPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPLLLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQKKIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQRRDDEFYKTPSLSSSGSSDGGTRPSSSQQGFGDDEACSMDTNGGGSHHHHHHHH

Expression System Baculovirus-InsectCells
Molecular Weight

111kDa (Reducing)

Purity >90% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer 20mMTris,500mM Nacl,10%Glycerol,3mM DTT, pH8.0
Stability & Storage

·12 months from date of receipt, -20 to -70 °C as supplied.
·1 month, 2 to 8 °C under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.

Reference

Biochem Biophys Res Commun. 2006 Jan 20;339(3):731-6.
Oncogenesis. 2017 Jun 12;6(6):e348.

Background

Usp4 is an oncogenic protein, because its expression with a strong promoter results in the tumorigenic transformation of NIH3T3 cells injected into nude mice. Although the structure of Usp4 is that of a deubiquitinating enzyme, neither its precise function in mammalian cells nor the mechanism of Usp4-mediated tumorigenesis is known. Usp4 functions as a deubiquitinating enzyme in human HEK293T cells and its isopeptidase activity deconjugates ubiquitin specifically from a Usp4- interacting protein Ro52.

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SKU: 61998181160

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4.9 ★★★★★
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Bill_in_Louisiana
Lowell, US
★★★★★ 3
The dog loves 'em
Color: Blue
The dog loves the balls, and they're the right size for my German Shepherd. Lost a couple of starts because they're not very durable, the "teeth" are easily broken off, so I am frequently finding "lost teeth" across the house; the squeakers also cannot hold up to my dog's aggressive chewing. I would still buy them again, as like I said, my dog love 'em!
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Reviewed in the United States on February 15, 2026
S
Verified Purchase
Sara
Carnegie, US
★★★★★ 5
Squeaky Spiky Ball (Submitted by OG, The Conqueror)
Size: 4.5 Set of 4
FIVE OUT OF FIVE PAWS. THIS IS THE GREATEST BALL EVER MADE. My name is OG, and I am a machine built for destruction. For years, I have systematically dismantled every supposed "heavy-duty" toy that dared cross my path. They all fail. They all surrender. But this Spiky Ball? This is my worthy adversary. This is The One. If you have mighty jaws like mine, this isn’t just a toy—it’s a commitment. The Aesthetics & Grip (5/5 Jaws) This ball is bright orange. This is important because it means my Dog-Parent cannot pretend they don't see it when I drop it, covered in drool, directly on their laptop. The spikes are the best part. They are not soft and pointless like some other toys. These spikes dig right into my gums. It's the perfect texture for a serious, focused chew session. Whether I'm running full-speed or we are locked in a heavy-duty Tug-of-War, those spikes give me the grip I need to apply maximum rotational torque. This ball never slips. It demands I bring my A-game. The Squeak: My Personal Battle Horn (5/5 Ears) The volume on this thing is set to LEGENDARY. They say a quiet dog is a happy dog. WRONG. A loud dog is an active, conquering dog. The squeak is sharp, loud, and glorious. It's not a gentle little peep—it's a declaration. When I hear it, I know the hunt is on. More importantly, when I make it squeak, the humans instantly know I require attention, praise, or the immediate launch of the ball across the yard. It is the best attention-getter I own. Durability: Unstoppable Force Meets Immovable Object (5/5 Eternal Glory) This ball is a mystery. It has no discernible weaknesses. I have performed the full Pitbull Destruction Protocol on this Spiky Ball every day for weeks: The Gnaw: Prolonged, focused effort to crack the surface—(Failure. It laughs.) The Shake: Head-whipping force designed to dislocate any internal components—(Failure. The squeak remains.) The Backyard Abandonment: Left in the rain and dirt for maximum entropy—(Failure. Still orange.) Most toys are a snack. This toy is a lifetime project. It truly is built for aggressive chewers, and I respect that. It is the only toy that challenges me. Recommendation If your dog is serious about their job (chewing, fetching, and being loud), you must buy this. It is the only thing that stands up to my power. It’s loud, it’s spiky, and it’s the best. Go buy it now, and tell them OG sent you. OG, currently performing a full-body gnaw and shake, signing off.
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Reviewed in the United States on November 11, 2025
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nolly
West Palm Beach, US
★★★★★ 5
Excellent product
Size: 4.5 Set of 4
Our service dog Max (named after Max Muncy 3rd baseman for the Dodgers) lives these balls. They are a sturdy product. Just what we needed for our Max.
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Reviewed in the United States on May 26, 2026
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J. Campbell
San Leandro, US
★★★★★ 5
Best squeaky ball for the buck!!
Size: 4.5 Set of 4
my 90lb Pit, LOVES these balls.. and they have been lasting for months!! The squeaker is ok, those are lasting a week or two.. but that's better than average for my guy. At $4 a ball in the 4 pack, it's a great deal for a dog that loves a new toy every month .. I give him one at a time, the 4 pack lasts for many months of fun.
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Reviewed in the United States on March 4, 2026
A
Verified Purchase
Amazon Customer
Draper, US
★★★★★ 5
Durable and Fun!
Size: 4.5 Set of 4
My dog LOVES these balls and barks with excitement when the box arrives. These balls are super durable and a great size that does not allow them to roll under cabinets and sofas.
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Reviewed in the United States on March 28, 2026

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