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Description
FGFR4/CD334 Recombinant Rabbit mAb (S-278-15)Product Specification Host Rabbit Antigen FGFR4 CD334 Synonyms JTK2, TKF Immunogen Recombinant Protein Location Endosome, Cell membrane, Endoplasmic reticulum Accession P22455 Clone Number S 278 15 Antibody Type Recombinant mAb Application WB, ICC Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months
Product Specification
| Host | Rabbit |
| Antigen | FGFR4/CD334 |
| Synonyms | JTK2, TKF |
| Immunogen | Recombinant Protein |
| Location | Endosome, Cell membrane, Endoplasmic reticulum |
| Accession | P22455 |
| Clone Number | S-278-15 |
| Antibody Type | Recombinant mAb |
| Application | WB, ICC |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| ICC | 1:250 | null |
Background
FGFR4 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
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